Take a look at the businesses making headlines earlier than the bell: Insmed — Shares surged greater than 26%. The worldwide biopharmaceutical firm introduced constructive outcomes Tuesday from a Part 2b research of treprostinil palmitil inhalation powder, a once-daily therapy for pulmonary arterial hypertension. J.M. Smucker — The meals firm’s inventory pulled again about 8% after its fourth-quarter income of $2.14 billion missed the consensus estimate of $2.18 billion, in keeping with FactSet. Earnings for the quarter beat expectations, nevertheless. The corporate’s steering additionally missed expectations. Taiwan Semiconductor Manufacturing — U.S.-listed shares of the chipmaker rose greater than 2% after its income for Could noticed a 39.6% improve in contrast with final 12 months. Income for January by means of Could was 42.6% larger than the identical interval a 12 months in the past. Casey’s Common Shops — The retail inventory jumped greater than 10% after stronger-than-expected fiscal fourth-quarter outcomes. Casey’s earned $2.63 per share on $3.99 billion in income. Analysts anticipated a revenue of $1.94 per share and $3.93 billion in income, per FactSet. The corporate additionally hiked its dividend by 14%. Apple — The iPhone maker’s inventory was barely larger in premarket buying and selling. It fell 1.2% within the earlier session, on the heels of its annual Worldwide Builders Convention on Monday. Whereas the corporate introduced a notable software program replace dubbed Liquid Glass, it did not reveal any important synthetic intelligence updates, underwhelming buyers . Tesla — Shares of the electrical car maker superior greater than 2% after ending Monday’s session greater than 4% larger. President Donald Trump stated Monday that he needs CEO Elon Musk “properly” and has no plans to discontinue Starlink on the White Home. The pair had a public feud final week. Musk responded to a video of the president’s remarks on X with a coronary heart emoji . Calavo Growers — The avocado distributor’s inventory plummeted greater than 14% after its earnings and income for the fiscal second quarter got here in weaker than anticipated. Calavo Growers posted adjusted earnings of 40 cents per share on $190.5 million in income, whereas analysts polled by FactSet have been in search of a revenue of 53 cents per share and $192.8 million in income. McDonald’s — The fast-food chain’s shares dropped practically 2% in premarket buying and selling after Redburn Atlantic double downgraded the inventory to a promote score on declining foot site visitors. The Wall Road agency additionally cited issues round GLP-1 weight problems medicine, pricing and tempered development expectations. — CNBC’s Jesse Pound and Yun Li contributed reporting.